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Biomarkers of mitotoxicity after acute liver injury: Further insights into the interpretation of glutamate dehydrogenase

BACKGROUND: Acetaminophen (APAP) is a popular analgesic, but overdose causes acute liver injury and sometimes death. Decades of research have revealed that mitochondrial damage is central in the mechanisms of toxicity in rodents, but we know much less about the role of mitochondria in humans. Due to...

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Detalles Bibliográficos
Publicado en:J Clin Transl Res
Main Authors: McGill, Mitchell R., Jaeschke, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado: Whioce Publishing Pte. Ltd. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8132186/
https://ncbi.nlm.nih.gov/pubmed/34027202
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