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The CNOT4 Subunit of the CCR4‐NOT Complex is Involved in mRNA Degradation, Efficient DNA Damage Repair, and XY Chromosome Crossover during Male Germ Cell Meiosis

The CCR4‐NOT complex is a major mRNA deadenylase in eukaryotes, comprising the catalytic subunits CNOT6/6L and CNOT7/8, as well as CNOT4, a regulatory subunit with previously undetermined functions. These subunits have been hypothesized to play synergistic biochemical functions during development. C...

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Udgivet i:Adv Sci (Weinh)
Main Authors: Dai, Xing‐Xing, Jiang, Yu, Gu, Jia‐Hui, Jiang, Zhi‐Yan, Wu, Yun‐Wen, Yu, Chao, Yin, Hao, Zhang, Jue, Shi, Qing‐Hua, Shen, Li, Sha, Qian‐Qian, Fan, Heng‐Yu
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8132151/
https://ncbi.nlm.nih.gov/pubmed/34026442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202003636
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