Smoothened inhibition leads to decreased cell proliferation and suppressed tissue fibrosis in the development of benign prostatic hyperplasia

Benign prostatic hyperplasia (BPH) is a common disease in aging males. It has been proven that the Hedgehog (HH) is implied as an effective and fundamental regulatory growth factor signal for organogenesis, homeostasis, and regeneration. Smoothened (SMO), as the major control point of HH signals, ac...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Liu, Jianmin, Yin, Jing, Chen, Ping, Liu, Daoquan, He, Weixiang, Li, Yan, Li, Mingzhou, Fu, Xun, Zeng, Guang, Guo, Yuming, Wang, Xinghuan, DiSanto, Michael E., Zhang, Xinhua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131753/
https://ncbi.nlm.nih.gov/pubmed/34006832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00501-4
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