Nicotine aggravates vascular adiponectin resistance via ubiquitin-mediated adiponectin receptor degradation in diabetic Apolipoprotein E knockout mouse

There is limited and discordant evidence on the role of nicotine in diabetic vascular disease. Exacerbated endothelial cell dysregulation in smokers with diabetes is associated with the disrupted adipose function. Adipokines possess vascular protective, anti-inflammatory, and anti-diabetic propertie...

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Publié dans:Cell Death Dis
Auteurs principaux: Gao, Jia, Fan, Jianghong, Meng, Zhijun, Wang, Rui, Liu, Caihong, Liu, Jing, Liang, Bin, Wang, Jing, Xie, Yaoli, Zhao, Jing, Guo, Rui, Zhao, Jianli, Ma, Xinliang, Jiao, Xiangying, Cao, Jimin, Wang, Yajing
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131622/
https://ncbi.nlm.nih.gov/pubmed/34006831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03772-y
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