Adiponectin aggravates bone erosion by promoting osteopontin production in synovial tissue of rheumatoid arthritis

BACKGROUND: We have previously reported that adiponectin (AD), an adipokine that is secreted by adipocytes, correlates well with progressive bone erosion in rheumatoid arthritis (RA). The exact mechanism of AD in promoting joint destruction remains unclear. Osteopontin (OPN) is required for osteocla...

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Bibliografski detalji
Izdano u:Arthritis Res Ther
Glavni autori: Qian, Jie, Xu, Lingxiao, Sun, Xiaoxuan, Wang, Yani, Xuan, Wenhua, Zhang, Qian, Zhao, Pengfei, Wu, Qin, Liu, Rui, Che, Nan, Wang, Fang, Tan, Wenfeng, Zhang, Miaojia
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806355/
https://ncbi.nlm.nih.gov/pubmed/29422077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1526-y
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