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Tubulin binding potentially clears up Bortezomib and Carfilzomib differential neurotoxic effect
Proteasome inhibitors (PIs) represent the gold standard in the treatment of multiple myeloma. Among PIs, Bortezomib (BTZ) is frequently used as first line therapy, but peripheral neuropathy (PN), occurring approximately in 50% of patients, impairs their life, representing a dose-limiting toxicity. C...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8131610/ https://ncbi.nlm.nih.gov/pubmed/34006972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89856-3 |
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