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Gene-level metagenomic architectures across diseases yield high-resolution microbiome diagnostic indicators

We propose microbiome disease “architectures”: linking >1 million microbial features (species, pathways, and genes) to 7 host phenotypes from 13 cohorts using a pipeline designed to identify associations that are robust to analytical model choice. Here, we quantify conservation and heterogeneity...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Tierney, Braden T., Tan, Yingxuan, Kostic, Aleksandar D., Patel, Chirag J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131609/
https://ncbi.nlm.nih.gov/pubmed/34006865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23029-8
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