Perfluoroalkyl substance pollutants activate the innate immune system through the AIM2 inflammasome

Perfluoroalkyl substances (PFAS) are widely used in various manufacturing processes. Accumulation of these chemicals has adverse effects on human health, including inflammation in multiple organs, yet how PFAS are sensed by host cells, and how tissue inflammation eventually incurs, is still unclear....

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Udgivet i:Nat Commun
Main Authors: Wang, Li-Qiu, Liu, Tao, Yang, Shuai, Sun, Lin, Zhao, Zhi-Yao, Li, Li-Yue, She, Yuan-Chu, Zheng, Yan-Yan, Ye, Xiao-Yan, Bao, Qing, Dong, Guang-Hui, Li, Chun-Wei, Cui, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131593/
https://ncbi.nlm.nih.gov/pubmed/34006824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23201-0
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