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D614G substitution at the hinge region enhances the stability of trimeric SARS-CoV-2 spike protein

Mutations in the spike protein of SARS-CoV-2 are the major causes for the modulation of ongoing COVID-19 infection. Currently, the D614G substitution in the spike protein has become dominant worldwide. It is associated with higher infectivity than the ancestral (D614)variant. We demonstrate using Ga...

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Vydáno v:Bioinformation
Hlavní autoři: Yazhini, Arangasamy, Sidhanta, Das Swayam Prakash, Srinivasan, Narayanaswamy
Médium: Artigo
Jazyk:Inglês
Vydáno: Biomedical Informatics 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131580/
https://ncbi.nlm.nih.gov/pubmed/34092964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630017439
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