Small-molecule inhibition of APE1 induces apoptosis, pyroptosis, and necroptosis in non-small cell lung cancer

Apurinic/apyrimidinic endonuclease 1 (APE1) plays a critical role in the base excision repair (BER) pathway, which is responsible for the excision of apurinic sites (AP sites). In non-small cell lung cancer (NSCLC), APE1 is highly expressed and associated with poor patient prognosis. The suppression...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: Long, Kaili, Gu, Lili, Li, Lulu, Zhang, Ziyu, Li, Enjie, Zhang, Yilan, He, Lingfeng, Pan, Feiyan, Guo, Zhigang, Hu, Zhigang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2021
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131371/
https://ncbi.nlm.nih.gov/pubmed/34006852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03804-7
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia