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Early nucleolar responses differentiate mechanisms of cell death induced by oxaliplatin and cisplatin

Recent reports provide evidence that the platinum chemotherapeutic oxaliplatin causes cell death via ribosome biogenesis stress, while cisplatin causes cell death via the DNA damage response (DDR). Underlying differences in mechanisms that might initiate disparate routes to cell death by these two b...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Sutton, Emily C., DeRose, Victoria J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131322/
https://ncbi.nlm.nih.gov/pubmed/33819479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100633
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