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PIM447 inhibits oncogenesis and potentiates cisplatin effects in hepatoblastoma
BACKGROUND: Novel therapies are needed for patients with hepatoblastoma due to an increasing incidence of disease and poor prognosis for advanced, refractory, and recurrent disease. PIM kinases promote tumorigenesis in hepatoblastoma. A novel PIM inhibitor, PIM447, has shown promise in inhibiting on...
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| Publicado no: | J Pediatr Surg |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8131223/ https://ncbi.nlm.nih.gov/pubmed/33762119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2021.02.039 |
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