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Mechanistic Toxicity Tests Based on an Adverse Outcome Pathway Network for Hepatic Steatosis
Risk assessors use liver endpoints in rodent toxicology studies to assess the safety of chemical exposures. Yet, rodent endpoints may not accurately reflect human responses. For this reason and others, human-based in vitro models are being developed and anchored to adverse outcome pathways to better...
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| Publicado no: | Toxicol Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8130650/ https://ncbi.nlm.nih.gov/pubmed/28903485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx121 |
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