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Predicting the Probability That a Chemical Causes Steatosis Using Adverse Outcome Pathway Bayesian Networks (AOPBNs)

Adverse Outcome Pathway Bayesian Networks (AOPBNs) are a promising avenue for developing predictive toxicology and risk assessment tools based on Adverse Outcome Pathways (AOPs). Here we describe a process for developing AOPBNs. AOPBNs use causal networks and Bayesian statistics to integrate evidenc...

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Detalhes bibliográficos
Publicado no:Risk Anal
Main Authors: Burgoon, Lyle D., Angrish, Michelle, Garcia-Reyero, Natalia, Pollesch, Nathan, Zupanic, Anze, Perkins, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397752/
https://ncbi.nlm.nih.gov/pubmed/31721239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/risa.13423
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