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Small-Molecule Inhibitors of the Coronavirus Spike – ACE2 Protein-Protein Interaction as Blockers of Viral Attachment and Entry for SARS-CoV-2

Inhibitors of the protein-protein interaction (PPI) between the SARS-CoV-2 spike protein and human ACE2 (hACE2), which acts as a ligand-receptor pair that initiates the viral attachment and cellular entry of this coronavirus causing the ongoing COVID-19 pandemic, are of considerable interest as pote...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Bojadzic, Damir, Alcazar, Oscar, Chen, Jinshui, Chuang, Sung-Ting, Capcha, Jose M. Condor, Shehadeh, Lina A., Buchwald, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130611/
https://ncbi.nlm.nih.gov/pubmed/33979123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.1c00070
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