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Estimating colocalization probability from limited summary statistics
BACKGROUND: Colocalization is a statistical method used in genetics to determine whether the same variant is causal for multiple phenotypes, for example, complex traits and gene expression. It provides stronger mechanistic evidence than shared significance, which can be produced through separate cau...
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| Udgivet i: | BMC Bioinformatics |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8130535/ https://ncbi.nlm.nih.gov/pubmed/34000989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-021-04170-z |
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