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Leveraging epigenetics to enhance the efficacy of immunotherapy

BACKGROUND: Epigenetic mechanisms regulate chromatin accessibility patterns that govern interaction of transcription machinery with genes and their cis-regulatory elements. Mutations that affect epigenetic mechanisms are common in cancer. Because epigenetic modifications are reversible many anticanc...

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Bibliografiske detaljer
Udgivet i:Clin Epigenetics
Main Authors: Licht, Jonathan D., Bennett, Richard L.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130138/
https://ncbi.nlm.nih.gov/pubmed/34001289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01100-x
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