LpxT-Dependent Phosphorylation of Lipid A in Escherichia coli Increases Resistance to Deoxycholate and Enhances Gut Colonization

The cell surface of Gram-negative bacteria usually exhibits a net negative charge mostly conferred by lipopolysaccharides (LPS). This property sensitizes bacterial cells to cationic antimicrobial peptides, such as polymyxin B, by favoring their binding to the cell surface. Gram-negative bacteria can...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Tian, Xudong, Manat, Guillaume, Gasiorowski, Elise, Auger, Rodolphe, Hicham, Samia, Mengin-Lecreulx, Dominique, Boneca, Ivo Gomperts, Touzé, Thierry
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129183/
https://ncbi.nlm.nih.gov/pubmed/34017319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2021.676596
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