12-Hydroxyeicosapentaenoic acid inhibits foam cell formation and ameliorates high-fat diet-induced pathology of atherosclerosis in mice

Atherosclerosis is a chronic inflammatory disease associated with macrophage aggregate and transformation into foam cells. In this study, we sought to investigate the impact of dietary intake of ω3 fatty acid on the development of atherosclerosis, and demonstrate the mechanism of action by identifyi...

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Publicado en:Sci Rep
Main Authors: Nagatake, Takahiro, Shibata, Yuki, Morimoto, Sakiko, Node, Eri, Sawane, Kento, Hirata, So-ichiro, Adachi, Jun, Abe, Yuichi, Isoyama, Junko, Saika, Azusa, Hosomi, Koji, Tomonaga, Takeshi, Kunisawa, Jun
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129127/
https://ncbi.nlm.nih.gov/pubmed/34001916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89707-1
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