Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma

The mechanisms driving therapeutic resistance and poor outcomes of mantle cell lymphoma (MCL) are incompletely understood. We characterize the cellular and molecular heterogeneity within and across patients and delineate the dynamic evolution of tumor and immune cell compartments at single cell reso...

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發表在:Nat Commun
Main Authors: Zhang, Shaojun, Jiang, Vivian Changying, Han, Guangchun, Hao, Dapeng, Lian, Junwei, Liu, Yang, Cai, Qingsong, Zhang, Rongjia, McIntosh, Joseph, Wang, Ruiping, Dang, Minghao, Dai, Enyu, Wang, Yuanxin, Santos, David, Badillo, Maria, Leeming, Angela, Chen, Zhihong, Hartig, Kimberly, Bigcal, John, Zhou, Jia, Kanagal-Shamanna, Rashmi, Ok, Chi Young, Lee, Hun, Steiner, Raphael E., Zhang, Jianhua, Song, Xingzhi, Nair, Ranjit, Ahmed, Sairah, Rodriquez, Alma, Thirumurthi, Selvi, Jain, Preetesh, Wagner-Bartak, Nicolaus, Hill, Holly, Nomie, Krystle, Flowers, Christopher, Futreal, Andrew, Wang, Linghua, Wang, Michael
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128874/
https://ncbi.nlm.nih.gov/pubmed/34001881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22872-z
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