Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma

The mechanisms driving therapeutic resistance and poor outcomes of mantle cell lymphoma (MCL) are incompletely understood. We characterize the cellular and molecular heterogeneity within and across patients and delineate the dynamic evolution of tumor and immune cell compartments at single cell reso...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Zhang, Shaojun, Jiang, Vivian Changying, Han, Guangchun, Hao, Dapeng, Lian, Junwei, Liu, Yang, Cai, Qingsong, Zhang, Rongjia, McIntosh, Joseph, Wang, Ruiping, Dang, Minghao, Dai, Enyu, Wang, Yuanxin, Santos, David, Badillo, Maria, Leeming, Angela, Chen, Zhihong, Hartig, Kimberly, Bigcal, John, Zhou, Jia, Kanagal-Shamanna, Rashmi, Ok, Chi Young, Lee, Hun, Steiner, Raphael E., Zhang, Jianhua, Song, Xingzhi, Nair, Ranjit, Ahmed, Sairah, Rodriquez, Alma, Thirumurthi, Selvi, Jain, Preetesh, Wagner-Bartak, Nicolaus, Hill, Holly, Nomie, Krystle, Flowers, Christopher, Futreal, Andrew, Wang, Linghua, Wang, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128874/
https://ncbi.nlm.nih.gov/pubmed/34001881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22872-z
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