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CADASIL from Bench to Bedside: Disease Models and Novel Therapeutic Approaches

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a monogenic disease caused by NOTCH3 mutations and characterized by typical clinical, neuroradiological, and pathological features. NOTCH3 belongs to a family of highly conserved transmembrane rec...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Manini, Arianna, Pantoni, Leonardo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128844/
https://ncbi.nlm.nih.gov/pubmed/33464533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-021-02282-4
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