Novel pathological features and potential therapeutic approaches for CADASIL: insights obtained from a mouse model of CADASIL

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common condition of hereditary stroke and vascular dementia. CADASIL is caused by Notch3 mutation, leading to progressive degeneration of vascular smooth muscle cells (vSMCs) of the small...

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Bibliografiske detaljer
Udgivet i:Ther Targets Neurol Dis
Main Authors: Liu, Xiao-Yun, Gonzalez-Toledo, Maria E., Fagan, Austin, Duan, Wei-Ming, Liu, Yanying, Zhang, Siyuan, Li, Bin, Piao, Chun-Shu, Nelson, Lila, Zhao, Li-Ru
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078431/
https://ncbi.nlm.nih.gov/pubmed/30090853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14800/ttnd.434
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