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Novel pathological features and potential therapeutic approaches for CADASIL: insights obtained from a mouse model of CADASIL
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common condition of hereditary stroke and vascular dementia. CADASIL is caused by Notch3 mutation, leading to progressive degeneration of vascular smooth muscle cells (vSMCs) of the small...
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Publicado no: | Ther Targets Neurol Dis |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6078431/ https://ncbi.nlm.nih.gov/pubmed/30090853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14800/ttnd.434 |
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