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SAAMBE-SEQ: a sequence-based method for predicting mutation effect on protein–protein binding affinity
MOTIVATION: Vast majority of human genetic disorders are associated with mutations that affect protein–protein interactions by altering wild-type binding affinity. Therefore, it is extremely important to assess the effect of mutations on protein–protein binding free energy to assist the development...
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| 發表在: | Bioinformatics |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8128451/ https://ncbi.nlm.nih.gov/pubmed/32866236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa761 |
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