Bifidobacterium dentium-derived y-glutamylcysteine suppresses ER-mediated goblet cell stress and reduces TNBS-driven colonic inflammation

Endoplasmic reticulum (ER) stress compromises the secretion of MUC2 from goblet cells and has been linked with inflammatory bowel disease (IBD). Although Bifidobacterium can beneficially modulate mucin production, little work has been done investigating the effects of Bifidobacterium on goblet cell...

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Detalhes bibliográficos
Publicado no:Gut Microbes
Main Authors: Engevik, Melinda A., Herrmann, Beatrice, Ruan, Wenly, Engevik, Amy C., Engevik, Kristen A., Ihekweazu, Faith, Shi, Zhongcheng, Luck, Berkley, Chang-Graham, Alexandra L., Esparza, Magdalena, Venable, Susan, Horvath, Thomas D., Haidacher, Sigmund J., Hoch, Kathleen M., Haag, Anthony M., Schady, Deborah A., Hyser, Joseph M., Spinler, Jennifer K., Versalovic, James
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128206/
https://ncbi.nlm.nih.gov/pubmed/33985416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19490976.2021.1902717
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