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Human-Derived Bifidobacterium dentium Modulates the Mammalian Serotonergic System and Gut–Brain Axis

BACKGROUND & AIMS: The human gut microbiota can regulate production of serotonin (5-hydroxytryptamine [5-HT]) from enterochromaffin cells. However, the mechanisms underlying microbial-induced serotonin signaling are not well understood. METHODS: Adult germ-free mice were treated with sterile med...

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Pubblicato in:Cell Mol Gastroenterol Hepatol
Autori principali: Engevik, Melinda A., Luck, Berkley, Visuthranukul, Chonnikant, Ihekweazu, Faith D., Engevik, Amy C., Shi, Zhongcheng, Danhof, Heather A., Chang-Graham, Alexandra L., Hall, Anne, Endres, Bradley T., Haidacher, Sigmund J., Horvath, Thomas D., Haag, Anthony M., Devaraj, Sridevi, Garey, Kevin W., Britton, Robert A., Hyser, Joseph M., Shroyer, Noah F., Versalovic, James
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683275/
https://ncbi.nlm.nih.gov/pubmed/32795610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.08.002
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