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Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases
NIK is a key kinase required for the activation of alternative NF-κB signaling pathways. Overactivation of NIK in patients has been observed and is implicated in the pathogenesis of inflammatory diseases, B-cell malignances, and solid tumors. Over the past decade, inhibition of NIK overactivation wi...
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| Publicado no: | RSC Med Chem |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
RSC
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8128072/ https://ncbi.nlm.nih.gov/pubmed/34046627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00361a |
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