Catalytic subunits of the phosphatase calcineurin interact with NF-κB-inducing kinase (NIK) and attenuate NIK-dependent gene expression

Nuclear factor (NF)-κB-inducing kinase (NIK) is a serine/threonine kinase that activates NF-κB pathways, thereby regulating a wide variety of immune systems. Aberrant NIK activation causes tumor malignancy, suggesting a requirement for precise regulation of NIK activity. To explore novel interacting...

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Publicado no:Sci Rep
Main Authors: Shinzawa, Miho, Konno, Hiroyasu, Qin, Junwen, Akiyama, Nobuko, Miyauchi, Maki, Ohashi, Hiroyuki, Miyamoto-Sato, Etsuko, Yanagawa, Hiroshi, Akiyama, Taishin, Inoue, Jun-ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377069/
https://ncbi.nlm.nih.gov/pubmed/26029823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10758
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