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Wedelolactone improves the renal injury induced by lipopolysaccharide in HK-2 cells by upregulation of protein tyrosine phosphatase non-receptor type 2

OBJECTIVE: To explore the effects of wedelolactone (WEL) on sepsis-induced renal injury in the human renal proximal tubular epithelial cell line HK-2. METHODS: HK-2 cells were stimulated by 1 µg/ml lipopolysaccharide (LPS) to trigger renal injury in vitro. HK-2 cells were pretreated with or without...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Int Med Res
Hauptverfasser: Zhi, Deyuan, Zhang, Meng, Lin, Jin, Liu, Pei, Wang, Yajun, Duan, Meili
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8127797/
https://ncbi.nlm.nih.gov/pubmed/33983070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/03000605211012665
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