Deletion of Protein Tyrosine Phosphatase Nonreceptor Type 2 in Intestinal Epithelial Cells Results in Upregulation of the Related Phosphatase Protein Tyrosine Phosphatase Nonreceptor Type 23

BACKGROUND/AIMS: Knockdown of protein tyrosine phosphatase nonreceptor type 2 (PTPN2) exaggerates IFN-γ-induced intestinal barrier defects, but mice constitutively lacking PTPN2 in epithelial cells (PTPN2xVilCre mice) do not show changes in epithelial function or enhanced susceptibility to experimen...

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Bibliografiske detaljer
Udgivet i:Inflamm Intest Dis
Main Authors: Ulugöl, Sima, Hering, Larissa, Manzini, Roberto, Montalban Arques, Ana, Gottier, Claudia, Lang, Silvia, Scharl, Michael, Spalinger, Marianne R.
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2019
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Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537469/
https://ncbi.nlm.nih.gov/pubmed/31172009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000499157
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