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Palmitate-TLR4 Signaling Regulates the Histone Demethylase, JMJD3, in Macrophages and Impairs Diabetic Wound Healing

Chronic macrophage inflammation is a hallmark of type 2 diabetes (T2D) and linked to the development of secondary diabetic complications. T2D is characterized by excess concentrations of saturated fatty acids (SFA) that activate innate immune inflammatory responses, however mechanism(s) by which SFA...

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Bibliografske podrobnosti
izdano v:Eur J Immunol
Main Authors: Davis, Frank M., denDekker, Aaron, Joshi, Amrita D., Wolf, Sonya J., Audu, Christopher, Melvin, William J., Mangum, Kevin, O’Riordan, Mary, Kunkel, Steven L., Gallagher, Katherine A.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8127612/
https://ncbi.nlm.nih.gov/pubmed/32662520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.202048651
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