A Surgical Window Trial Evaluating Medroxyprogesterone Acetate with or without Entinostat in Patients with Endometrial Cancer and Validation of Biomarkers of Cellular Response

OBJECTIVE: This surgical window of opportunity (window) study assessed short-term effect of medroxyprogesterone acetate (MPA) alone vs MPA plus histone deacetylase (HDAC) inhibitor entinostat on regulation of progesterone receptor (PR) in women with newly diagnosed endometrioid endometrial adenocarc...

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Bibliografske podrobnosti
izdano v:Clin Cancer Res
Main Authors: Duska, Linda R., Filiaci, Virginia L., Walker, Joan L., Holman, Laura L., Hill, Emily K., Moore, Richard G., Ring, Kari, Pearl, Michael L., Muller, Carolyn Y., Kushnir, Christina L., Lankes, Heather A., Samuelson, Megan I., Carrick, Kelley S., Rajan, Anand, Rodgers, William H., Kohn, Elise C., Piekarz, Richard, Leslie, Kimberly K.
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8127359/
https://ncbi.nlm.nih.gov/pubmed/33766814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-4618
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