Comprehensive Molecular Characterization and Response to Therapy in FH-Deficient Renal Cell Carcinoma

PURPOSE: Fumarate hydratase-deficient renal cell carcinoma (FH-RCC) is a rare, aggressive form of RCC associated with hereditary leiomyomatosis and RCC syndrome (HLRCC). Evidence for systemic therapy efficacy is lacking. METHODS: We studied clinical and genomic characteristics of FH-RCC, including r...

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Bibliografske podrobnosti
izdano v:Clin Cancer Res
Main Authors: Gleeson, Jack P., Nikolovski, Ines, Dinatale, Renzo, Zucker, Mark, Knezevic, Andrea, Patil, Sujata, Ged, Yasser, Kotecha, Ritesh R, Shapnik, Natalie, Murray, Samuel, Russo, Paul, Coleman, Jonathan, Lee, Chung Han, Stadler, Zsofia K, Hakimi, A. Ari, Feldman, Darren R, Motzer, Robert J, Reznik, Ed, Voss, Martin H, Chen, Ying-Bei, Carlo, Maria I
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8127353/
https://ncbi.nlm.nih.gov/pubmed/33658299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-4367
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