Comprehensive Molecular Characterization and Response to Therapy in FH-Deficient Renal Cell Carcinoma

PURPOSE: Fumarate hydratase-deficient renal cell carcinoma (FH-RCC) is a rare, aggressive form of RCC associated with hereditary leiomyomatosis and RCC syndrome (HLRCC). Evidence for systemic therapy efficacy is lacking. METHODS: We studied clinical and genomic characteristics of FH-RCC, including r...

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Bibliografiske detaljer
Udgivet i:Clin Cancer Res
Main Authors: Gleeson, Jack P., Nikolovski, Ines, Dinatale, Renzo, Zucker, Mark, Knezevic, Andrea, Patil, Sujata, Ged, Yasser, Kotecha, Ritesh R, Shapnik, Natalie, Murray, Samuel, Russo, Paul, Coleman, Jonathan, Lee, Chung Han, Stadler, Zsofia K, Hakimi, A. Ari, Feldman, Darren R, Motzer, Robert J, Reznik, Ed, Voss, Martin H, Chen, Ying-Bei, Carlo, Maria I
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8127353/
https://ncbi.nlm.nih.gov/pubmed/33658299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-4367
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