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Differences in Recycling of Apolipoprotein E3 and E4—LDL Receptor Complexes—A Mechanistic Hypothesis

Apolipoprotein E (ApoE) is a protein that plays an important role in the transport of fatty acids and cholesterol and in cellular signaling. On the surface of the cells, ApoE lipoparticles bind to low density lipoprotein receptors (LDLR) that mediate the uptake of the lipids and downstream signaling...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kim, Meewhi, Bezprozvanny, Ilya
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126166/
https://ncbi.nlm.nih.gov/pubmed/34068576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22095030
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