Homologous Recombination Repair Deficiency and Implications for Tumor Immunogenicity

SIMPLE SUMMARY: Cells possess several pathways that repair DNA damage. One of these pathways is homologous recombination repair (HR), a pathway responsible for the repair of double-strand DNA breaks. In cancer, HR is sometimes dysfunctional, leading to genomic instability. The genomic instability ob...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancers (Basel)
Prif Awduron: van Wilpe, Sandra, Tolmeijer, Sofie H., Koornstra, Rutger H. T., de Vries, I. Jolanda M., Gerritsen, Winald R., Ligtenberg, Marjolijn, Mehra, Niven
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Review
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8124836/
https://ncbi.nlm.nih.gov/pubmed/34067105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13092249
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