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Targeting CDK9 for Anti-Cancer Therapeutics

SIMPLE SUMMARY: CDK9, in combination with Cyclin T1, is one of the major regulators of RNA Polymerase II mediated productive transcription of critical genes in any cell. The activity of CDK9 is significantly up-regulated in a wide variety of cancer entities, to aid in the overexpression of genes res...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Mandal, Ranadip, Becker, Sven, Strebhardt, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8124690/
https://ncbi.nlm.nih.gov/pubmed/34062779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13092181
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