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RRx-001 Increases Erythrocyte Preferential Adhesion to the Tumor Vasculature

Red blood cells (RBCs) serve a variety of functions beyond mere oxygen transport both in health and pathology. Notably, RRx-001, a minimally toxic pleiotropic anticancer agent with macrophage activating and vascular normalization properties currently in Phase III trials, induces modification to RBCs...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Jani, Vinay P., Asaro, Robert, Oronsky, Bryan, Cabrales, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8124275/
https://ncbi.nlm.nih.gov/pubmed/33946824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094713
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