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The Anti-Cancer Effects of a Zotarolimus and 5-Fluorouracil Combination Treatment on A549 Cell-Derived Tumors in BALB/c Nude Mice

Zotarolimus is a semi-synthetic derivative of rapamycin and a novel immunosuppressive agent used to prevent graft rejection. The pharmacological pathway of zotarolimus restricts the kinase activity of the mammalian target of rapamycin (mTOR), which potentially leads to reductions in cell division, c...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wu, Ching-Feng, Wu, Ching-Yang, Chiou, Robin Y.-Y., Yang, Wei-Cheng, Lin, Chuen-Fu, Wang, Chao-Min, Hou, Po-Hsun, Lin, Tzu-Chun, Kuo, Chan-Yen, Chang, Geng-Ruei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123799/
https://ncbi.nlm.nih.gov/pubmed/33925400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094562
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