The Anti-Cancer Effects of a Zotarolimus and 5-Fluorouracil Combination Treatment on A549 Cell-Derived Tumors in BALB/c Nude Mice

Zotarolimus is a semi-synthetic derivative of rapamycin and a novel immunosuppressive agent used to prevent graft rejection. The pharmacological pathway of zotarolimus restricts the kinase activity of the mammalian target of rapamycin (mTOR), which potentially leads to reductions in cell division, c...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Wu, Ching-Feng, Wu, Ching-Yang, Chiou, Robin Y.-Y., Yang, Wei-Cheng, Lin, Chuen-Fu, Wang, Chao-Min, Hou, Po-Hsun, Lin, Tzu-Chun, Kuo, Chan-Yen, Chang, Geng-Ruei
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123799/
https://ncbi.nlm.nih.gov/pubmed/33925400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094562
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