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Development of Novel Potential Pleiotropic Compounds of Interest in Alzheimer’s Disease Treatment through Rigidification Strategy

The development of Multi-Target Directed Ligand is of clear interest for the treatment of multifactorial pathology such as Alzheimer’s disease (AD). In this context, acetylcholinesterase (AChE) inhibitors have been modulated in order to generate novel pleiotropic compounds targeting a second protein...

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Foilsithe in:Molecules
Main Authors: Lecoutey, Cédric, Legay, Rémi, Davis, Audrey, Sopková-de Oliveira Santos, Jana, Dallemagne, Patrick, Rochais, Christophe
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123621/
https://ncbi.nlm.nih.gov/pubmed/33926141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26092536
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