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Development of Novel Potential Pleiotropic Compounds of Interest in Alzheimer’s Disease Treatment through Rigidification Strategy

The development of Multi-Target Directed Ligand is of clear interest for the treatment of multifactorial pathology such as Alzheimer’s disease (AD). In this context, acetylcholinesterase (AChE) inhibitors have been modulated in order to generate novel pleiotropic compounds targeting a second protein...

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Bibliographic Details
Published in:Molecules
Main Authors: Lecoutey, Cédric, Legay, Rémi, Davis, Audrey, Sopková-de Oliveira Santos, Jana, Dallemagne, Patrick, Rochais, Christophe
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123621/
https://ncbi.nlm.nih.gov/pubmed/33926141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26092536
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