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Efficacy of the Piperidine Nitroxide 4-MethoxyTEMPO in Ameliorating Serum Amyloid A-Mediated Vascular Inflammation

Intracellular redox imbalance in endothelial cells (EC) can lead to endothelial dysfunction, which underpins cardiovascular diseases (CVD). The acute phase serum amyloid A (SAA) elicits inflammation through stimulating production of reactive oxygen species (ROS). The cyclic nitroxide 4-MethoxyTEMPO...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Martin, Nathan J., Chami, Belal, Vallejo, Abigail, Mojadadi, Albaraa A., Witting, Paul K., Ahmad, Gulfam
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123591/
https://ncbi.nlm.nih.gov/pubmed/33925294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094549
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