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New Cocrystals of Antipsychotic Drug Aripiprazole: Decreasing the Dissolution through Cocrystallization

Cocrystallization is an important route to tuning the solubility in drugs development, including improving and reducing. Five cocrystals of aripiprazole (ARI) with resveratrol (RSV) and kaempferol (KAE), ARI-RSV, ARI(2)-RSV(1)·MeOH, ARI-KAE, ARI-KAE·EtOH, ARI-KAE·IPA, were synthesized and characteri...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Liu, Wenwen, Ma, Ru, Liang, Feifei, Duan, Chenxin, Zhang, Guisen, Chen, Yin, Hao, Chao
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122301/
https://ncbi.nlm.nih.gov/pubmed/33919175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26092414
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