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Quinacrine-Induced Autophagy in Ovarian Cancer Triggers Cathepsin-L Mediated Lysosomal/Mitochondrial Membrane Permeabilization and Cell Death

SIMPLE SUMMARY: Ovarian cancer (OC) is the most common cause of cancer-related deaths among women worldwide, and its incidence has been increasing and has continued to prove resistant to a variety of therapeutics. This observation is principally disturbing given the amount of money invested in ident...

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Publicado en:Cancers (Basel)
Autores principales: Thirusangu, Prabhu, Pathoulas, Christopher L., Ray, Upasana, Xiao, Yinan, Staub, Julie, Jin, Ling, Khurana, Ashwani, Shridhar, Viji
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122252/
https://ncbi.nlm.nih.gov/pubmed/33919392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13092004
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