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Iridium-catalyzed C−H methylation and d(3)-methylation of benzoic acids with application to late-stage functionalizations
Late-stage functionalization (LSF) has over the past years emerged as a powerful approach in the drug discovery process. At its best, it allows for rapid access to new analogues from a single drug-like molecule, bypassing the need for de novo synthesis. To be successful, methods able to tolerate the...
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| Pubblicato in: | iScience |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8122115/ https://ncbi.nlm.nih.gov/pubmed/34027322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102467 |
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