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High-throughput sequencing defines donor and recipient HLA B-cell epitope frequencies for prospective matching in transplantation

Compatibility for human leukocyte antigen (HLA) genes between transplant donors and recipients improves graft survival but prospective matching is rarely performed due to the vast heterogeneity of this gene complex. To reduce complexity, we have combined next-generation sequencing and in silico mapp...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Tran, Jenny N., Günther, Oliver P., Sherwood, Karen R., Fenninger, Franz, Allan, Lenka L., Lan, James, Sapir-Pichhadze, Ruth, Duquesnoy, Rene, Claas, Frans, Marsh, Steven G. E., McMaster, W. Robert, Keown, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121953/
https://ncbi.nlm.nih.gov/pubmed/33990681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01989-3
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