DEFECTIVE IMMUNOMETABOLISM PATHWAYS IN CYSTIC FIBROSIS MACROPHAGES

BACKGROUND: Mitochondria play a key role in immune defense pathways, particularly for macrophages. We and others have previously demonstrated that cystic fibrosis (CF) macrophages exhibit weak autophagy activity and exacerbated inflammatory responses. Previous studies have revealed that mitochondria...

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Detalhes bibliográficos
Publicado no:J Cyst Fibros
Main Authors: Hamilton, Kaitlin, Krause, Kathrin, Badr, Asmaa, Daily, Kylene, Estfanous, Shady, Eltobgy, Mostafa, Khweek, Arwa Abu, Anne, Midhun N.K., Carafice, Cierra, Baetzhold, Daniel, Tonniges, Jeffrey R., Zhang, Xiaoli, Gavrilin, Mikhail A., Parinandi, Narasimham L., Amer, Amal O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121894/
https://ncbi.nlm.nih.gov/pubmed/33208300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2020.10.006
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