DEFECTIVE IMMUNOMETABOLISM PATHWAYS IN CYSTIC FIBROSIS MACROPHAGES

BACKGROUND: Mitochondria play a key role in immune defense pathways, particularly for macrophages. We and others have previously demonstrated that cystic fibrosis (CF) macrophages exhibit weak autophagy activity and exacerbated inflammatory responses. Previous studies have revealed that mitochondria...

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Publicat a:J Cyst Fibros
Autors principals: Hamilton, Kaitlin, Krause, Kathrin, Badr, Asmaa, Daily, Kylene, Estfanous, Shady, Eltobgy, Mostafa, Khweek, Arwa Abu, Anne, Midhun N.K., Carafice, Cierra, Baetzhold, Daniel, Tonniges, Jeffrey R., Zhang, Xiaoli, Gavrilin, Mikhail A., Parinandi, Narasimham L., Amer, Amal O.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121894/
https://ncbi.nlm.nih.gov/pubmed/33208300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2020.10.006
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