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Regulation of GC box activity by 8-oxoguanine

The oxidation-induced DNA modification 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) was recently implicated in the activation and repression of gene transcription. We aimed at a systematic characterisation of the impacts of 8-oxodG on the activity of a GC box placed upstream from the RNA polymerase...

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Pubblicato in:Redox Biol
Autori principali: Müller, Nadine, Khobta, Andriy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120935/
https://ncbi.nlm.nih.gov/pubmed/33965877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101997
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