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Regulation of GC box activity by 8-oxoguanine
The oxidation-induced DNA modification 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) was recently implicated in the activation and repression of gene transcription. We aimed at a systematic characterisation of the impacts of 8-oxodG on the activity of a GC box placed upstream from the RNA polymerase...
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| Publié dans: | Redox Biol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8120935/ https://ncbi.nlm.nih.gov/pubmed/33965877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101997 |
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